The objective of the present investigation was to prepare and evaluate an isabgol husk based directly compressible (DC) Adjuvant that can be used as matrixing agent using an agglomeration technique. Addition of hydroxy propyl methylcellulose was found necessary to improve cohesion. Lactose, calcium hydrogen Orthophosphate and Directly compressible vehicle, used along with isabgol in preparation of agglomerates. The agglomerates were evaluated for their flow properties. Tablets were prepared using 95% agglomerates and 5% domperidone, a poorly compressible drug, and were subjected to in vitro drug release study. Out of various formulations (F4) was recognised as an ideal formulation. All the formulations passes the limits.
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